MYLIP

Across TCGA cell cohorts, MYLIP mutation is significantly associated with the drug of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYLIP-associated genes across cancer lineages are GSK2801, SU11274, and Gallibiscoquinazole. Each is linked with MYLIP in more than 1 cancer types. Because this analysis shows association rather than direction, both MYLIP-to-partner and partner-to-MYLIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2801 grouped by MYLIP-low versus MYLIP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLIP→partner) and Y-score (partner→MYLIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2801 →	+0.397	+2.649	.011	.046	3	1
LARGE_INTESTINE	SU11274 →	+0.427	+2.652	.040	.045	3	1
LARGE_INTESTINE	Gallibiscoquinazole →	+0.335	+2.649	.042	.046	2	1
LARGE_INTESTINE	CP724714 →	+0.345	+2.652	.040	.045	2	1
LARGE_INTESTINE	Dacarbazine →	+0.302	+2.777	.030	.038	1	1
LARGE_INTESTINE	123138 →	+0.341	+2.649	.020	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

GSK2801 by MYLIP expression — LARGE_INTESTINE

Explore this box plot interactively →