Across TCGA patient cohorts, MYL4 mutation is significantly associated with the RNA expression of many other genes, with 210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYL4-associated genes across cancer lineages are SNORD114-1, SNRPGP7, and NTMT1. Each is linked with MYL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL4-to-partner and partner-to-MYL4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL4→partner) and Y-score (partner→MYL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORD114-1 →	+0.770	+5.124	<.001	.008	3	2
HNSC	SNRPGP7 →	+0.596	+5.736	<.001	.003	3	2
UCEC	NTMT1 →	+0.711	+3.338	.004	.005	3	2
UCEC	MIR1251 →	+0.180	+4.300	.002	.005	3	2
LUSC	RN7SKP298 →	+0.225	+7.924	.002	.008	3	2
UCEC	VDAC1P5 →	+0.105	+2.363	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 210 associations by consensus.

Exploration

MYL4 survival (RNA) · tumor vs normal (RNA) · all MYL4 data types