MYL2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYL2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,113 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MYL2-associated genes across cancer lineages are TRAJ41, CISD1P1, and PLA2G4C. Each is linked with MYL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL2-to-partner and partner-to-MYL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYL2 versus TRAJ41 in BRCA, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL2→partner) and Y-score (partner→MYL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATRAJ41 →+1.310+2.543.006.00132
BRCACISD1P1 →+0.550+2.343.007.00732
HNSCPLA2G4C →+0.558+1.135<.001.00132
HNSCNT5C1A →+0.906+1.437<.001<.00132
HNSCLINC02428 →-0.938-1.081.001.00132
HNSCSLCO1A2 →-1.163-1.356.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,113 associations by consensus.

MYL2 vs TRAJ41 — BRCA

Per-sample scatter of MYL2 vs TRAJ41 in BRCA (Pearson r = 0.82).

Explore this scatter interactively →

Exploration