MYL12AP1

Across TCGA pan-cancer cohorts, MYL12AP1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MYL12AP1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MYL12AP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYL12AP1 expression acts as an unfavorable survival marker, although some lineages such as THCA and PAAD show a favorable association.

ACC, THCA, and MESO are the cancer types where MYL12AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Quartile	II,III,IV	0.205	0.804	.001	64	view →
THCA	DFS	Tertile	All	0.962	0.893	.001	50	view →
MESO	OS	Quartile	II,III,IV	0.321	0.620	.002	44	view →
LGG	DFS	Quartile	All	0.291	0.464	<.001	31	view →
PAAD	DFS	Quartile	II,III,IV	0.441	0.253	.002	24	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
UCS	DFS	Median	IV	0.909	0.416	.008	18	view →
LUAD	DFS	Median	II,III,IV	0.619	0.415	.006	16	view →
KIRC	DFS	Quartile	III,IV	0.550	0.267	.023	14	view →
KIRP	OS	Tertile	II,III,IV	0.858	0.565	.038	14	view →
PRAD	OS	Tertile	All	0.968	1.000	.004	12	view →
DLBC	DFS	Median	All	0.355	0.858	.009	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MYL12AP1–ACC (OS)

Open the ACC breakdown →