MYL12AP1

Across TCGA pan-cancer cohorts, MYL12AP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MYL12AP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MYL12AP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYL12AP1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

COAD, HNSC, and LUSC are the cancer types where MYL12AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYL12AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.321	.017	4	view →
HNSC	Female	IV	+0.170	.035	2	view →
LUSC	Male	All	−0.139	.008	2	view →
THCA	Male	All	+0.168	.012	1	view →
KIRP	Female	All	+0.138	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MYL12AP1–COAD

Open the COAD breakdown →