MYL12A

Across TCGA patient cohorts, MYL12A mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYL12A-associated genes across cancer lineages are RNU1-57P, RN7SL230P, and MIR4510. Each is linked with MYL12A in more than 1 cancer types. Because this analysis shows association rather than direction, both MYL12A-to-partner and partner-to-MYL12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-57P grouped by MYL12A-low versus MYL12A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYL12A→partner) and Y-score (partner→MYL12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-57P →	+0.262	+5.148	<.001	.002	3	2
UCEC	RN7SL230P →	+0.446	+3.233	.001	.005	3	1
UCEC	MIR4510 →	+0.260	+4.132	<.001	.009	3	1
UCEC	SNRPCP20 →	+0.280	+3.463	.003	.003	3	1
UCEC	WDR7-OT1 →	+0.138	+3.179	<.001	.006	3	1
BLCA	RNU6-1318P →	+0.418	+5.588	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

RNU1-57P by MYL12A expression — UCEC

Explore this box plot interactively →