MYH9

Across TCGA patient cohorts, MYH9 protein abundance is significantly associated with the RNA expression of many other genes, with 18,043 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYH9-associated genes across cancer lineages are MYL9, SERPINE1, and COL1A1. Each is linked with MYH9 in more than 7 cancer types. Because this analysis shows association rather than direction, both MYH9-to-partner and partner-to-MYH9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYH9 versus MYL9 in GBM, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH9→partner) and Y-score (partner→MYH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYL9 →	+1.260	+0.474	<.001	<.001	3	8
GBM	SERPINE1 →	+1.904	+0.640	<.001	<.001	3	8
OV	COL1A1 →	+2.567	+0.478	<.001	<.001	3	8
OV	SPARC →	+1.908	+0.651	<.001	<.001	3	8
OV	FN1 →	+2.477	+0.522	<.001	<.001	3	8
HNSC	TSHZ3 →	+0.833	+0.321	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,043 associations by consensus.

MYH9 vs MYL9 — GBM

Explore this scatter interactively →