MYH9

Across TCGA cell cohorts, MYH9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,955 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MYH9-associated GO terms across cancer lineages are Caveolin-mediated endocytosis, Caveola assembly, and Regulation of cell-substrate adhesion. Each is linked with MYH9 in more than 17 cancer types. Because this analysis shows association rather than direction, both MYH9-to-partner and partner-to-MYH9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveolin-mediated endocytosis grouped by MYH9-low versus MYH9-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH9→partner) and Y-score (partner→MYH9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Caveolin-mediated endocytosis →	+0.223	+1.445	<.001	<.001	3	18
LIVER	Caveola assembly →	+0.263	+1.955	<.001	<.001	3	18
BONE	Regulation of cell-substrate adhesion →	+0.125	+2.105	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Platelet aggregation →	+0.120	+1.260	<.001	.004	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.191	+1.319	.001	<.001	3	17
BONE	Regulation of plasma membrane repair →	+0.349	+2.451	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,955 associations by consensus.

Caveolin-mediated endocytosis by MYH9 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →