MYH13

Across TCGA cell cohorts, MYH13 RNA expression is significantly associated with the go_rna of many other GO terms, with 402 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MYH13-associated GO terms across cancer lineages are Positive regulation of telomere maintenance via telomerase, Positive regulation of hormone metabolic process, and Detection of mechanical stimulus. Each is linked with MYH13 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYH13-to-partner and partner-to-MYH13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere maintenance via telomerase grouped by MYH13-low versus MYH13-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH13→partner) and Y-score (partner→MYH13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of telomere maintenance via telomerase →	+0.048	+0.036	.006	.009	3	3
CNS	Positive regulation of hormone metabolic process →	-0.094	-0.030	.006	.006	3	3
CNS	Detection of mechanical stimulus →	-0.081	-0.038	<.001	<.001	3	3
CNS	Mitochondrial membrane organization →	+0.047	+0.031	<.001	.004	3	3
BLOOD_Lymphoma	Positive regulation of retinoic acid receptor signaling pathway →	+0.096	+0.009	.005	.006	3	3
BLOOD_Myeloma	Regulation of cytokine production involved in inflammatory response →	+0.071	+0.069	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

Positive regulation of telomere maintenance via telomerase by MYH13 expression — CNS

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