MYH1

Across TCGA cell cohorts, MYH1 mutation is significantly associated with the RNA expression of many other genes, with 836 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYH1-associated genes across cancer lineages are OR6V1, HBG1, and PRKRIP1. Each is linked with MYH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYH1-to-partner and partner-to-MYH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by MYH1-low versus MYH1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYH1→partner) and Y-score (partner→MYH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR6V1 →	+0.069	+5.369	<.001	.004	3	3
OESOPHAGUS	HBG1 →	+0.090	+3.845	.007	.001	3	3
SKIN	PRKRIP1 →	-0.448	-3.569	.001	<.001	3	3
PANCREAS	ZNF729 →	+0.006	+5.614	<.001	.002	3	2
BLOOD_Myeloma	NPY →	+0.062	+3.906	<.001	.009	3	2
BREAST	TMEM233 →	+0.064	+4.232	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 836 associations by consensus.

OR6V1 by MYH1 expression — SOFT_TISSUE

Explore this box plot interactively →