MYG1

Across TCGA patient cohorts, MYG1 mutation is significantly associated with the RNA expression of many other genes, with 77 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYG1-associated genes across cancer lineages are COPS8P1, ACTR3BP6, and RNA5SP205. Each is linked with MYG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYG1-to-partner and partner-to-MYG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPS8P1 grouped by MYG1-low versus MYG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYG1→partner) and Y-score (partner→MYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS8P1 →	+0.161	+2.842	<.001	.007	3	2
STAD	ACTR3BP6 →	+0.027	+5.187	<.001	.007	3	2
KIRC	RNA5SP205 →	+0.331	+6.293	<.001	.001	3	2
SKCM	CTBP2P9 →	+0.100	+5.080	<.001	.004	3	1
UCEC	NUTF2P8 →	+0.170	+3.661	<.001	.001	3	1
UCEC	RNVU1-28 →	+1.101	+2.635	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

COPS8P1 by MYG1 expression — UCEC

Explore this box plot interactively →