MYG1-AS1

Across TCGA pan-cancer cohorts, MYG1-AS1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of MYG1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where MYG1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYG1-AS1 is over-expressed in tumor.

HNSC, COAD, and BLCA are the cancer types where MYG1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYG1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	IV	+1.090	<.001	12	view →
COAD	Male	III,IV	+1.352	<.001	11	view →
BLCA	Male	III,IV	+1.081	<.001	11	view →
KIRC	Male	IV	+1.330	<.001	10	view →
LIHC	All	II,III,IV	+1.021	<.001	9	view →
KIRP	Male	II,III,IV	+1.011	<.001	9	view →
STAD	Female	All	+0.731	<.001	8	view →
THCA	Female	II,III,IV	+0.497	<.001	8	view →
UCEC	All	II,III,IV	+0.598	.002	6	view →
BRCA	All	III,IV	+0.448	<.001	6	view →
LUAD	Female	All	+0.620	<.001	5	view →
CHOL	Male	All	+2.266	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

MYG1-AS1–HNSC

Open the HNSC breakdown →