MYF6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYF6 mutation is significantly associated with the RNA expression of many other genes, with 3,046 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYF6-associated genes across cancer lineages are RNA5SP412, BRI3BP, and TTC19. Each is linked with MYF6 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYF6-to-partner and partner-to-MYF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by MYF6-low versus MYF6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF6→partner) and Y-score (partner→MYF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP412 →+0.414+1.797.001.00534
UCECBRI3BP →+0.636+2.949<.001<.00134
COADTTC19 →+0.700+3.335<.001.00533
UCECHSPA9 →+0.558+2.938<.001<.00133
COADOXSM →+0.562+3.348<.001.00533
COADCHCHD4 →+0.513+3.362<.001.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,046 associations by consensus.

RNA5SP412 by MYF6 expression — UCEC

Box plot of RNA5SP412 in MYF6-low vs MYF6-high samples in UCEC.

Explore this box plot interactively →

Exploration