MYF6

Across TCGA cell cohorts, MYF6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible MYF6-associated genes across cancer lineages are IFNA4, GLYATL1B, and ACER1. Each is linked with MYF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYF6-to-partner and partner-to-MYF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA4 grouped by MYF6-low versus MYF6-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYF6→partner) and Y-score (partner→MYF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNA4 →	+0.150	+4.321	<.001	.009	3	1
CNS	GLYATL1B →	+0.029	+4.315	.004	.006	3	1
LARGE_INTESTINE	ACER1 →	+0.075	+3.145	.004	.004	3	1
LUNG_NSCLC_LUAD	OR8B8 →	+0.019	+3.734	.001	.006	3	1
CNS	CYP4A22 →	+0.018	+4.345	<.001	.005	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IFNA4 by MYF6 expression — CNS

Explore this box plot interactively →