MYEF2

Across TCGA patient cohorts, MYEF2 mutation is significantly associated with the RNA expression of many other genes, with 2,901 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYEF2-associated genes across cancer lineages are RNA5SP411, RNA5SP435, and OR6K1P. Each is linked with MYEF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYEF2-to-partner and partner-to-MYEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by MYEF2-low versus MYEF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYEF2→partner) and Y-score (partner→MYEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.902	+1.570	<.001	.001	3	4
LUSC	RNA5SP435 →	+0.594	+4.042	<.001	.001	3	3
LUAD	OR6K1P →	+0.047	+5.924	<.001	<.001	3	3
UCEC	ZFX-AS1 →	+0.279	+1.736	<.001	.003	3	3
UCEC	RNA5SP413 →	+1.046	+1.791	<.001	<.001	3	3
CESC	RN7SL813P →	+0.121	+3.688	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

RNA5SP411 by MYEF2 expression — UCEC

Explore this box plot interactively →