MYD88

Across TCGA patient cohorts, MYD88 mutation is significantly associated with the RNA expression of many other genes, with 939 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYD88-associated genes across cancer lineages are RNU6-693P, MIR7976, and SPCS2P2. Each is linked with MYD88 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYD88-to-partner and partner-to-MYD88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-693P grouped by MYD88-low versus MYD88-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYD88→partner) and Y-score (partner→MYD88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-693P →	+0.834	+5.721	<.001	.001	3	3
LIHC	MIR7976 →	+0.431	+5.268	<.001	.006	3	2
UCEC	SPCS2P2 →	+0.072	+2.613	<.001	.007	3	2
UCEC	RN7SL44P →	+0.220	+2.709	<.001	.006	3	2
LIHC	RN7SKP14 →	+0.285	+5.544	<.001	.004	3	2
COAD	RNU6-666P →	+0.986	+6.734	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 939 associations by consensus.

RNU6-693P by MYD88 expression — COAD

Explore this box plot interactively →