MYCT1

Across TCGA patient cohorts, MYCT1 mutation is significantly associated with the RNA expression of many other genes, with 556 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MYCT1-associated genes across cancer lineages are MIR4484, RNA5SP391, and SNORD116-14. Each is linked with MYCT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MYCT1-to-partner and partner-to-MYCT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4484 grouped by MYCT1-low versus MYCT1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCT1→partner) and Y-score (partner→MYCT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4484 →	+0.185	+2.137	.002	.005	3	3
HNSC	RNA5SP391 →	+0.155	+6.366	<.001	<.001	3	2
SKCM	SNORD116-14 →	+0.568	+2.442	<.001	<.001	3	2
HNSC	RNU6-12P →	+0.348	+5.124	<.001	<.001	3	2
SKCM	MIR5192 →	+0.278	+2.041	<.001	.003	3	2
UCEC	MIR3153 →	+1.232	+3.519	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

MIR4484 by MYCT1 expression — SKCM

Explore this box plot interactively →