MYCNOS

Across TCGA patient cohorts, MYCNOS RNA expression is significantly associated with the protein abundance of many other proteins, with 9,339 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYCNOS-associated proteins across cancer lineages are DNMT3A, HDGFL3, and ZNF428. Each is linked with MYCNOS in more than 2 cancer types. Because this analysis shows association rather than direction, both MYCNOS-to-partner and partner-to-MYCNOS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYCNOS versus DNMT3A in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCNOS→partner) and Y-score (partner→MYCNOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNMT3A →	+0.511	+0.299	.001	.002	3	3
GBM	HDGFL3 →	+0.692	+0.497	<.001	<.001	3	3
GBM	ZNF428 →	+0.489	+0.454	<.001	<.001	3	3
GBM	ARL3 →	+0.390	+0.509	<.001	<.001	3	3
OV	ZNF687 →	+0.219	+0.317	.004	.002	3	3
OV	YWHAQ →	+0.365	+0.385	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,339 associations by consensus.

MYCNOS vs DNMT3A — OV

Explore this scatter interactively →