Across TCGA pan-cancer cohorts, MYCLP1 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of MYCLP1’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where MYCLP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYCLP1 is over-expressed in tumor.
LUSC are the cancer types where MYCLP1 tumor–normal differential expression is most reproducible.