MYCL

Across TCGA patient cohorts, MYCL RNA expression is significantly associated with the protein abundance of many other proteins, with 13,540 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MYCL-associated proteins across cancer lineages are NEK6, ARHGAP18, and PALM2AKAP2_S393. Each is linked with MYCL in more than 3 cancer types. Because this analysis shows association rather than direction, both MYCL-to-partner and partner-to-MYCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYCL versus NEK6 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCL→partner) and Y-score (partner→MYCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NEK6 →	-0.411	-0.853	<.001	<.001	3	4
LSCC	ARHGAP18 →	-0.387	-1.143	<.001	<.001	3	4
GBM	PALM2AKAP2_S393 →	-0.606	-0.985	<.001	<.001	3	4
LSCC	XPO5 →	+0.520	+0.859	<.001	<.001	3	4
LSCC	SPAST →	+0.317	+0.857	<.001	<.001	3	4
LSCC	ACO1_T628 →	-0.576	-1.185	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,540 associations by consensus.

MYCL vs NEK6 — GBM

Explore this scatter interactively →