MYCL-AS1

Across TCGA pan-cancer cohorts, MYCL-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated MYCL-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher MYCL-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYCL-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

MESO, HNSC, and KIRC are the cancer types where MYCL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Quartile	III,IV	0.332	0.756	<.001	70	view →
HNSC	DFS	Median	IV	0.516	0.268	<.001	63	view →
KIRC	DFS	Quartile	All	0.667	0.865	<.001	59	view →
THCA	OS	Quartile	II,III,IV	0.853	0.977	<.001	49	view →
ACC	DFS	Quartile	All	0.165	0.564	.002	33	view →
THYM	DFS	Tertile	II,III,IV	0.739	0.998	.003	30	view →
LAML	DFS	Median	All	0.268	0.472	.011	26	view →
SKCM	DFS	Median	All	0.678	0.558	.003	20	view →
LIHC	DFS	Median	III,IV	0.587	0.245	.003	15	view →
UCEC	DFS	Tertile	All	0.798	0.861	.027	12	view →
CHOL	DFS	Quartile	All	0.117	0.543	.007	10	view →
UVM	DFS	Quartile	III,IV	0.461	0.903	.012	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

MYCL-AS1–MESO (OS)

Open the MESO breakdown →