MYCL-AS1

Across TCGA pan-cancer cohorts, MYCL-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MYCL-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MYCL-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MYCL-AS1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, HNSC, and BLCA are the cancer types where MYCL-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYCL-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.210	<.001	10	view →
HNSC	All	II,III,IV	+0.123	<.001	8	view →
BLCA	All	III,IV	+0.755	.011	5	view →
LUSC	All	All	+0.276	<.001	5	view →
THCA	All	II,III,IV	−0.123	.008	4	view →
COAD	All	All	+0.105	.020	4	view →
UCEC	All	IV	+0.185	.033	2	view →
LIHC	All	All	+0.134	.012	2	view →
STAD	All	III,IV	+0.062	.033	1	view →
KIRC	All	IV	+0.049	.021	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MYCL-AS1–LUAD

Open the LUAD breakdown →