MYCBPAP

Across TCGA patient cohorts, MYCBPAP mutation is significantly associated with the RNA expression of many other genes, with 2,203 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYCBPAP-associated genes across cancer lineages are RPA3P2, MYO19, and XPNPEP1. Each is linked with MYCBPAP in more than 2 cancer types. Because this analysis shows association rather than direction, both MYCBPAP-to-partner and partner-to-MYCBPAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPA3P2 grouped by MYCBPAP-low versus MYCBPAP-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCBPAP→partner) and Y-score (partner→MYCBPAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RPA3P2 →	+0.079	+3.745	.005	.005	3	3
UCEC	MYO19 →	+0.365	+2.161	.004	<.001	3	3
UCEC	XPNPEP1 →	+0.353	+2.513	.003	<.001	3	3
UCEC	MLX →	+0.389	+2.119	.001	<.001	3	3
UCEC	DHDDS →	+0.360	+1.625	<.001	.005	3	3
UCEC	ACYP1 →	+0.337	+3.234	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,203 associations by consensus.

RPA3P2 by MYCBPAP expression — LUAD

Explore this box plot interactively →