MYCBPAP

Across TCGA pan-cancer cohorts, MYCBPAP RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MYCBPAP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MYCBPAP RNA is repressed in tumor relative to normal tissue. In most cancer types MYCBPAP is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

KIRC, LIHC, and CHOL are the cancer types where MYCBPAP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYCBPAP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.229	<.001	11	view →
LIHC	Female	All	+0.073	<.001	7	view →
CHOL	All	All	+0.508	.003	4	view →
LUSC	Female	II,III,IV	−0.650	<.001	3	view →
KICH	All	All	−0.309	.002	3	view →
THCA	All	All	−0.176	.010	3	view →
HNSC	Male	All	+0.122	.012	3	view →
UCEC	All	II,III,IV	−0.724	.046	2	view →
BLCA	All	All	+0.315	.012	2	view →
BRCA	All	III,IV	+0.238	.043	2	view →
KIRP	All	All	−0.195	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MYCBPAP–KIRC

Open the KIRC breakdown →