MYCBPAP

Across TCGA patient cohorts, MYCBPAP mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYCBPAP-associated genes across cancer lineages are A-Raf_pS299, FoxM1, and PCNA. Each is linked with MYCBPAP in more than 3 cancer types. Because this analysis shows association rather than direction, both MYCBPAP-to-partner and partner-to-MYCBPAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by MYCBPAP-low versus MYCBPAP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCBPAP→partner) and Y-score (partner→MYCBPAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.119	-1.700	.002	.042	3	3
UCEC	FoxM1 →	+0.185	+1.459	.027	.012	3	3
COAD	PCNA →	+0.267	+3.330	.022	.005	3	3
UCEC	ATM →	-0.623	-2.000	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+1.111	+2.178	.002	.035	3	3
UCEC	Cyclin-B1 →	+0.700	+2.321	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

A-Raf_pS299 by MYCBPAP expression — UCEC

Explore this box plot interactively →