MYCBP2-AS2

Across TCGA pan-cancer cohorts, MYCBP2-AS2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MYCBP2-AS2 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MYCBP2-AS2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MYCBP2-AS2 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, SKCM, and UVM are the cancer types where MYCBP2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.601	0.458	.004	76	view →
SKCM	OS	Quartile	III,IV	0.884	0.609	<.001	50	view →
UVM	DFS	Tertile	III,IV	0.282	0.664	.001	46	view →
LUAD	DFS	Median	II,III,IV	0.394	0.169	.005	43	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
THYM	OS	Tertile	II,III,IV	0.839	1.000	.002	33	view →
LAML	DFS	Quartile	All	0.660	0.253	<.001	30	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.008	28	view →
COAD	DFS	Tertile	II,III,IV	0.229	0.521	.008	25	view →
HNSC	OS	Quartile	All	0.476	0.377	.018	24	view →
PAAD	OS	Quartile	II,III,IV	0.561	0.297	.010	19	view →
OV	OS	Quartile	All	0.782	0.872	.009	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MYCBP2-AS2–BLCA (DFS)

Open the BLCA breakdown →