MYCBP2-AS2

Across TCGA pan-cancer cohorts, MYCBP2-AS2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MYCBP2-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where MYCBP2-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types MYCBP2-AS2 is over-expressed in tumor, although a few such as BRCA and KIRP show the opposite, repressed pattern.

BRCA, KIRP, and COAD are the cancer types where MYCBP2-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYCBP2-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.216	.013	2	view →
KIRP	All	All	−0.117	.014	2	view →
COAD	All	III,IV	+0.093	.039	1	view →
KIRC	Male	III,IV	−0.080	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MYCBP2-AS2–BRCA

Open the BRCA breakdown →