Across TCGA patient cohorts, MYCBP mutation is significantly associated with the RNA expression of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYCBP-associated genes across cancer lineages are IGKV1OR-2, SSTR5, and BCRP6. Each is linked with MYCBP in more than 1 cancer types. Because this analysis shows association rather than direction, both MYCBP-to-partner and partner-to-MYCBP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCBP→partner) and Y-score (partner→MYCBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV1OR-2 →	+0.266	+2.715	.001	.006	3	1
UCEC	SSTR5 →	+0.873	+2.728	<.001	.009	3	1
UCEC	BCRP6 →	+0.081	+3.398	.001	.001	3	1
UCEC	MIR6803 →	+0.245	+5.671	<.001	<.001	3	1
UCEC	SNX3P1Y →	+0.199	+5.671	<.001	<.001	3	1
UCEC	IL26 →	+0.215	+3.901	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

MYCBP survival (RNA) · tumor vs normal (RNA) · all MYCBP data types