MYBPC2

Across TCGA patient cohorts, MYBPC2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,357 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYBPC2-associated genes across cancer lineages are PLEKHA8, POU6F2, and IMPG1. Each is linked with MYBPC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBPC2-to-partner and partner-to-MYBPC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYBPC2 versus PLEKHA8 in LSCC, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPC2→partner) and Y-score (partner→MYBPC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHA8 →	-0.947	-0.187	<.001	.005	3	2
LSCC	POU6F2 →	-2.260	-0.229	<.001	<.001	3	2
LSCC	IMPG1 →	-0.547	-0.217	.005	.007	3	2
LSCC	IGSF1 →	-2.102	-0.202	.004	.004	3	2
LSCC	ADAMTS20 →	-2.136	-0.263	<.001	.001	3	2
LSCC	EXTL2P1 →	-1.078	-0.230	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,357 associations by consensus.

MYBPC2 vs PLEKHA8 — LSCC

Explore this scatter interactively →