MYBBP1A

Across TCGA patient cohorts, MYBBP1A mutation is significantly associated with the RNA expression of many other genes, with 8,571 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBBP1A-associated genes across cancer lineages are PHF7, PSMC3IP, and UBASH3B. Each is linked with MYBBP1A in more than 3 cancer types. Because this analysis shows association rather than direction, both MYBBP1A-to-partner and partner-to-MYBBP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHF7 grouped by MYBBP1A-low versus MYBBP1A-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBBP1A→partner) and Y-score (partner→MYBBP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	PHF7 →	+0.445	+2.945	<.001	<.001	3	4
UCEC	PSMC3IP →	+0.537	+1.943	<.001	<.001	3	4
COAD	UBASH3B →	+0.668	+1.920	<.001	.009	3	4
STAD	TYW3 →	+0.523	+2.601	<.001	<.001	3	4
STAD	COQ2 →	+0.722	+3.281	<.001	<.001	3	4
UCEC	SLC25A17 →	+0.333	+1.351	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,571 associations by consensus.

PHF7 by MYBBP1A expression — STAD

Explore this box plot interactively →