MYBBP1A

Across TCGA patient cohorts, MYBBP1A mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBBP1A-associated genes across cancer lineages are eEF2, GAPDH, and MEK1. Each is linked with MYBBP1A in more than 4 cancer types. Because this analysis shows association rather than direction, both MYBBP1A-to-partner and partner-to-MYBBP1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by MYBBP1A-low versus MYBBP1A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBBP1A→partner) and Y-score (partner→MYBBP1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	eEF2 →	+0.334	+2.824	.014	.036	3	5
STAD	GAPDH →	+0.425	+2.807	<.001	.002	3	3
UCEC	MEK1 →	+0.405	+1.847	<.001	<.001	3	3
STAD	mTOR_pS2448 →	-0.141	-2.321	.018	.030	3	3
COAD	Caspase-7-cleavedD198 →	+1.393	+2.476	<.001	.009	3	3
UCEC	ATM →	-0.538	-1.669	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

eEF2 by MYBBP1A expression — BLCA

Explore this box plot interactively →