MYB-AS1

Across TCGA pan-cancer cohorts, MYB-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MYB-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher MYB-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYB-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and BRCA show a favorable association.

THCA, OV, and ACC are the cancer types where MYB-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	III,IV	0.670	0.871	<.001	99	view →
OV	OS	Tertile	II,III,IV	0.784	0.868	.002	66	view →
ACC	DFS	Tertile	All	0.121	0.644	.002	48	view →
READ	OS	Median	II,III,IV	0.851	0.458	.008	39	view →
BRCA	OS	Tertile	III,IV	0.918	0.718	<.001	36	view →
LAML	DFS	Median	All	0.681	0.463	.004	28	view →
CESC	DFS	Quartile	II,III,IV	0.643	0.830	.005	24	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
HNSC	DFS	Tertile	II,III,IV	0.816	0.662	.024	15	view →
THYM	OS	Median	II,III,IV	0.952	0.712	.005	13	view →
LGG	OS	Tertile	All	0.645	0.820	.007	12	view →
LUAD	DFS	Quartile	IV	0.412	0.906	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MYB-AS1–THCA (OS)

Open the THCA breakdown →