MYADM

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYADM mutation is significantly associated with the RNA expression of many other genes, with 3,836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYADM-associated genes across cancer lineages are RN7SL447P, RN7SL248P, and OR5M14P. Each is linked with MYADM in more than 2 cancer types. Because this analysis shows association rather than direction, both MYADM-to-partner and partner-to-MYADM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL447P grouped by MYADM-low versus MYADM-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYADM→partner) and Y-score (partner→MYADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL447P →+0.196+5.201<.001.00733
UCECRN7SL248P →+0.044+2.678<.001.00233
CESCOR5M14P →+0.085+5.539<.001.00432
UCECGCAT →+0.605+3.076<.001<.00132
UCECCCDC134 →+0.412+2.120.001<.00132
UCECL3MBTL2 →+0.370+2.110<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,836 associations by consensus.

RN7SL447P by MYADM expression — CESC

Box plot of RN7SL447P in MYADM-low vs MYADM-high samples in CESC.

Explore this box plot interactively →

Exploration