MXRA8

Across TCGA cell cohorts, MXRA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,945 significant associations in total. BONE shows the largest number of these associations.

The most reproducible MXRA8-associated GO terms across cancer lineages are Positive regulation of amyloid-beta clearance, Regulation of myoblast fusion, and Regulation of focal adhesion assembly. Each is linked with MXRA8 in more than 10 cancer types. Because this analysis shows association rather than direction, both MXRA8-to-partner and partner-to-MXRA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of amyloid-beta clearance grouped by MXRA8-low versus MXRA8-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MXRA8→partner) and Y-score (partner→MXRA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of amyloid-beta clearance →	+0.256	+2.558	<.001	<.001	3	11
OESOPHAGUS	Regulation of myoblast fusion →	+0.123	+2.608	.007	<.001	3	11
BONE	Regulation of focal adhesion assembly →	+0.206	+3.735	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction assembly →	+0.206	+3.735	<.001	<.001	3	10
BONE	Regulation of cell-substrate adhesion →	+0.115	+2.725	<.001	<.001	3	10
BONE	Regulation of cell-substrate junction organization →	+0.138	+2.536	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,945 associations by consensus.

Positive regulation of amyloid-beta clearance by MXRA8 expression — OESOPHAGUS

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