MXD4

Across TCGA cell cohorts, MXD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,528 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MXD4-associated GO terms across cancer lineages are Positive regulation of autophagy, Retrograde transport, endosome to Golgi, and Regulation of macroautophagy. Each is linked with MXD4 in more than 15 cancer types. Because this analysis shows association rather than direction, both MXD4-to-partner and partner-to-MXD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by MXD4-low versus MXD4-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD4→partner) and Y-score (partner→MXD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of autophagy →	+0.057	+1.674	<.001	<.001	3	16
STOMACH	Retrograde transport, endosome to Golgi →	+0.074	+1.193	.007	.001	3	16
OESOPHAGUS	Regulation of macroautophagy →	+0.073	+1.296	<.001	<.001	3	14
STOMACH	Cytosolic transport →	+0.068	+1.154	.005	<.001	3	14
KIDNEY	Process utilizing autophagic mechanism →	+0.066	+1.100	.003	.001	3	14
KIDNEY	Autophagy →	+0.066	+1.100	.003	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,528 associations by consensus.

Positive regulation of autophagy by MXD4 expression — OESOPHAGUS

Explore this box plot interactively →