MXD4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MXD4 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MXD4-associated genes across cancer lineages are OR51G2. Each is linked with MXD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both MXD4-to-partner and partner-to-MXD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51G2 grouped by MXD4-low versus MXD4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD4→partner) and Y-score (partner→MXD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR51G2 →+0.019+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR51G2 by MXD4 expression — BLOOD_Leukemia

Box plot of OR51G2 in MXD4-low vs MXD4-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration