Across TCGA patient cohorts, MXD3 protein abundance is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. OV shows the largest number of these associations.

The most reproducible MXD3-associated genes across cancer lineages are SERPINA4, INSM1, and SNORD9. Each is linked with MXD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MXD3-to-partner and partner-to-MXD3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD3→partner) and Y-score (partner→MXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERPINA4 →	+0.075	+0.492	<.001	.009	3	1
OV	INSM1 →	+0.125	+0.492	.001	.009	3	1
OV	SNORD9 →	+1.305	+0.492	.001	.009	3	1
OV	SP9 →	+2.290	+0.492	.001	.009	3	1
OV	RPL18AP14 →	+0.265	+0.492	<.001	.009	3	1
OV	RPS3AP41 →	+0.185	+0.492	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

MXD3 survival (RNA) · tumor vs normal (RNA) · all MXD3 data types