MX1

Across TCGA patient cohorts, MX1 mutation is significantly associated with the immune_cell of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MX1-associated genes across cancer lineages are CD8+ naive T-cells, DC, and MSC. Each is linked with MX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MX1-to-partner and partner-to-MX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by MX1-low versus MX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MX1→partner) and Y-score (partner→MX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.020	+2.354	.030	.018	3	3
COAD	DC →	+0.015	+2.286	.045	.020	3	2
COAD	MSC →	+0.258	+3.026	.001	.019	3	2
UCEC	MEP →	+0.028	+2.254	.003	.005	3	2
UCEC	Basophils →	+0.153	+2.459	.009	.019	3	2
UCEC	pDC →	+0.045	+2.254	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CD8+ naive T-cells by MX1 expression — UCEC

Explore this box plot interactively →