MX1

Across TCGA cell cohorts, MX1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible MX1-associated genes across cancer lineages are FNDC9, ADGB, and OR1G1. Each is linked with MX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MX1-to-partner and partner-to-MX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FNDC9 grouped by MX1-low versus MX1-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MX1→partner) and Y-score (partner→MX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FNDC9 →	+0.024	+3.857	<.001	.002	3	2
OESOPHAGUS	ADGB →	+0.026	+3.857	<.001	.002	3	1
OESOPHAGUS	OR1G1 →	+0.043	+3.392	<.001	.007	3	1
OESOPHAGUS	VHLL →	+0.101	+3.716	<.001	.005	3	1
OESOPHAGUS	USP17L1 →	+0.114	+3.836	<.001	.004	3	1
LARGE_INTESTINE	TECRL →	+0.014	+3.977	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

FNDC9 by MX1 expression — OESOPHAGUS

Explore this box plot interactively →