MVK

Across TCGA patient cohorts, MVK protein abundance is significantly associated with the RNA expression of many other genes, with 14,492 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MVK-associated genes across cancer lineages are DHCR24, MMAB, and MSMO1. Each is linked with MVK in more than 7 cancer types. Because this analysis shows association rather than direction, both MVK-to-partner and partner-to-MVK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MVK versus DHCR24 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MVK→partner) and Y-score (partner→MVK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DHCR24 →	+1.131	+0.442	<.001	.001	3	8
BRCA	MMAB →	+0.772	+0.625	<.001	<.001	3	8
HNSC	MSMO1 →	+0.741	+0.368	<.001	<.001	3	6
COAD	HMGCR →	+0.727	+0.322	<.001	<.001	3	5
CCRCC	TSPAN1 →	+2.372	+0.452	<.001	<.001	3	5
LSCC	EBP →	+0.691	+0.496	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,492 associations by consensus.

MVK vs DHCR24 — BRCA

Explore this scatter interactively →