MVD

Across TCGA patient cohorts, MVD mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible MVD-associated genes across cancer lineages are GMP and Astrocytes. Each is linked with MVD in more than 1 cancer types. Because this analysis shows association rather than direction, both MVD-to-partner and partner-to-MVD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by MVD-low versus MVD-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MVD→partner) and Y-score (partner→MVD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GMP →	+0.060	+3.562	.034	.015	3	1
COAD	Astrocytes →	+0.048	+2.692	.018	.048	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GMP by MVD expression — COAD

Explore this box plot interactively →