MUSK

Across TCGA patient cohorts, MUSK protein abundance is significantly associated with the RNA expression of many other genes, with 4,984 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MUSK-associated genes across cancer lineages are DPP4, DPP4-DT, and CFAP221. Each is linked with MUSK in more than 6 cancer types. Because this analysis shows association rather than direction, both MUSK-to-partner and partner-to-MUSK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUSK versus DPP4 in LUAD, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUSK→partner) and Y-score (partner→MUSK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DPP4 →	+2.185	+1.223	<.001	<.001	3	7
LUAD	DPP4-DT →	+1.663	+1.285	<.001	<.001	3	4
LUAD	CFAP221 →	+1.570	+1.153	<.001	.001	3	3
GBM	FA2H →	-1.335	-1.049	.003	.007	3	2
LUAD	MRPL4 →	+0.426	+0.825	<.001	<.001	3	2
LUAD	GLCCI1 →	+0.800	+0.862	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,984 associations by consensus.

MUSK vs DPP4 — LUAD

Explore this scatter interactively →