MUC7

Across TCGA cell cohorts, MUC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 320 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MUC7-associated GO terms across cancer lineages are Lung cell differentiation, Lung epithelial cell differentiation, and Negative regulation of hydrogen peroxide biosynthetic process. Each is linked with MUC7 in more than 2 cancer types. Because this analysis shows association rather than direction, both MUC7-to-partner and partner-to-MUC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lung cell differentiation grouped by MUC7-low versus MUC7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC7→partner) and Y-score (partner→MUC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Lung cell differentiation →	-0.116	-0.078	.004	.009	3	3
CNS	Lung epithelial cell differentiation →	-0.116	-0.078	.004	.009	3	3
SKIN	Negative regulation of hydrogen peroxide biosynthetic process →	+0.180	+0.669	<.001	.002	3	3
BREAST	Membrane depolarization during cardiac muscle cell action potential →	-0.650	-0.056	.001	.005	3	2
CNS	Negative regulation of melanin biosynthetic process →	+0.106	+0.078	<.001	.009	3	2
SKIN	T cell differentiation in thymus →	-0.050	-0.639	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 320 associations by consensus.

Lung cell differentiation by MUC7 expression — CNS

Explore this box plot interactively →