MUC5B

Across TCGA cell cohorts, MUC5B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,298 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MUC5B-associated GO terms across cancer lineages are Regulation of single-species biofilm formation, Negative regulation of single-species biofilm formation, and Regulation of single-species biofilm formation in or on host organism. Each is linked with MUC5B in more than 10 cancer types. Because this analysis shows association rather than direction, both MUC5B-to-partner and partner-to-MUC5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of single-species biofilm formation grouped by MUC5B-low versus MUC5B-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC5B→partner) and Y-score (partner→MUC5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of single-species biofilm formation →	+1.399	+3.013	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Negative regulation of single-species biofilm formation →	+1.399	+3.013	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Regulation of single-species biofilm formation in or on host organism →	+1.399	+3.013	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Negative regulation of single-species biofilm formation in or on host organism →	+1.399	+3.013	<.001	<.001	3	11
PANCREAS	Cortical actin cytoskeleton organization →	+0.108	+1.843	<.001	.001	3	5
STOMACH	Disaccharide transport →	+0.794	+2.160	.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,298 associations by consensus.

Regulation of single-species biofilm formation by MUC5B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →