Across TCGA patient cohorts, MUC5AC protein abundance is significantly associated with the RNA expression of many other genes, with 6,691 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MUC5AC-associated genes across cancer lineages are AGR2, TSPAN1, and BPIFB1. Each is linked with MUC5AC in more than 4 cancer types. Because this analysis shows association rather than direction, both MUC5AC-to-partner and partner-to-MUC5AC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC5AC→partner) and Y-score (partner→MUC5AC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AGR2 →	+2.021	+1.344	<.001	<.001	3	5
LSCC	TSPAN1 →	+1.480	+0.907	<.001	<.001	3	5
HNSC	BPIFB1 →	+2.478	+0.785	.004	.002	3	5
LUAD	GCNT3 →	+1.930	+2.296	<.001	<.001	3	5
LUAD	TFF1 →	+2.658	+1.821	<.001	<.001	3	5
HNSC	SLC44A4 →	+1.264	+0.867	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,691 associations by consensus.

Exploration

MUC5AC survival (RNA) · tumor vs normal (RNA) · all MUC5AC data types