Across TCGA patient cohorts, MUC5AC mutation is significantly associated with the total protein of many other genes, with 66 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MUC5AC-associated genes across cancer lineages are eEF2, Caspase-7-cleavedD198, and Cyclin-E2. Each is linked with MUC5AC in more than 3 cancer types. Because this analysis shows association rather than direction, both MUC5AC-to-partner and partner-to-MUC5AC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC5AC→partner) and Y-score (partner→MUC5AC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.268	+1.700	.023	.040	3	4
UCEC	Caspase-7-cleavedD198 →	+0.515	+1.522	.008	.017	3	4
SKCM	Cyclin-E2 →	+0.153	+1.807	.006	.004	3	4
UCEC	JNK2 →	+0.326	+2.263	<.001	<.001	3	3
UCEC	Cyclin-B1 →	+0.546	+1.652	.003	.006	3	3
SKCM	XBP1 →	-0.220	-2.137	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

MUC5AC survival (RNA) · tumor vs normal (RNA) · all MUC5AC data types