MUC3A

Across TCGA patient cohorts, MUC3A protein abundance is significantly associated with the RNA expression of many other genes, with 1,927 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MUC3A-associated genes across cancer lineages are SLC5A1, PIP5K1B, and ATP8B3. Each is linked with MUC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC3A-to-partner and partner-to-MUC3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC3A versus SLC5A1 in LUAD, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC3A→partner) and Y-score (partner→MUC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC5A1 →	+1.475	+1.599	.007	.002	3	2
PDAC	PIP5K1B →	+1.003	+0.976	<.001	<.001	3	2
LUAD	ATP8B3 →	-0.647	-1.255	.002	.004	3	2
PDAC	HMGCS2 →	+2.010	+0.991	<.001	.001	3	2
LUAD	TPGS2 →	-0.475	-1.170	<.001	.003	3	2
LUAD	HNF1A →	+0.739	+1.637	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,927 associations by consensus.

MUC3A vs SLC5A1 — LUAD

Explore this scatter interactively →