MUC3A

Across TCGA cell cohorts, MUC3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,509 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MUC3A-associated GO terms across cancer lineages are Equilibrioception, Establishment of apical/basal cell polarity, and Establishment of epithelial cell apical/basal polarity. Each is linked with MUC3A in more than 8 cancer types. Because this analysis shows association rather than direction, both MUC3A-to-partner and partner-to-MUC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Equilibrioception grouped by MUC3A-low versus MUC3A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC3A→partner) and Y-score (partner→MUC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Equilibrioception →	+1.275	+2.554	<.001	<.001	3	9
SOFT_TISSUE	Establishment of apical/basal cell polarity →	-0.153	-1.005	<.001	<.001	3	8
LIVER	Establishment of epithelial cell apical/basal polarity →	-0.205	-1.846	.003	.003	3	7
STOMACH	GDP-L-fucose metabolic process →	+0.089	+2.133	<.001	<.001	3	7
BONE	Mineralocorticoid biosynthetic process →	+1.337	+1.919	<.001	<.001	3	7
SOFT_TISSUE	Muscle organ development →	-0.107	-0.681	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,509 associations by consensus.

Equilibrioception by MUC3A expression — LARGE_INTESTINE

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