MUC20

Across TCGA patient cohorts, MUC20 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,338 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MUC20-associated proteins across cancer lineages are SDCBP2, SAFB_S507, and TCEA3_S158. Each is linked with MUC20 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC20-to-partner and partner-to-MUC20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC20 versus SDCBP2 in LSCC, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC20→partner) and Y-score (partner→MUC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SDCBP2 →	+1.398	+1.513	<.001	<.001	3	2
LUAD	SAFB_S507 →	+0.445	+0.521	<.001	.001	3	1
LUAD	TCEA3_S158 →	+0.836	+0.536	<.001	<.001	3	1
LUAD	TNS1_S907 →	+0.890	+0.694	<.001	<.001	3	1
LUAD	PDLIM7_S274 →	+0.732	+0.708	<.001	<.001	3	1
LUAD	RANBP3_S211 →	+0.348	+0.527	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,338 associations by consensus.

MUC20 vs SDCBP2 — LSCC

Explore this scatter interactively →