MUC20-OT1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MUC20-OT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MUC20-OT1-associated proteins across cancer lineages are PRPF4, DHX9, and SF3B3. Each is linked with MUC20-OT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MUC20-OT1-to-partner and partner-to-MUC20-OT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC20-OT1 versus PRPF4 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC20-OT1→partner) and Y-score (partner→MUC20-OT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPRPF4 →+0.227+0.773<.001<.00135
GBMDHX9 →+0.235+0.609<.001<.00135
LSCCSF3B3 →+0.222+0.952<.001<.00135
LSCCAQR →+0.341+0.913<.001<.00134
HNSCNFIC →+0.437+0.881<.001<.00134
HNSCNIPBL →+0.328+1.155<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,292 associations by consensus.

MUC20-OT1 vs PRPF4 — LSCC

Per-sample scatter of MUC20-OT1 vs PRPF4 in LSCC (Pearson r = 0.48).

Explore this scatter interactively →

Exploration